Researchers have been on the hunt for new drugs to combat bacterial 'superbugs.' A new report describes success using gallium, a metal that bacteria confuse for iron, which they take up as a nutrient. Gallium, however, works as a Trojan horse, disrupting bacteria's ability to multiply. In mice, gallium cured lethal lung infections, and in a small test in humans with cystic fibrosis, gallium improved patients' lung function.
Researchers report that tweaking factors in a cystic fibrosis lung model, such as pH balance and oxygen, helped eradicate pathogenic bacteria while minimizing risks of antibiotic resistance and overgrowth of other microorganisms.
A new study suggests that infants, who are vulnerable to an array of infectious diseases, may have a microbial ally in keeping antibiotic-resistant infections at bay. Researchers found that children with higher gut levels of Bifidobacterium, a common commensal, had reduced abundance and lower frequency of the genes associated with antimicrobial resistance (AMR).
A new clinical trial shows that broadly neutralizing antibodies can suppress HIV for up to four months, far longer than currently available drugs.
People like the late Stephen Hawking are unable to speak because their muscles are paralyzed. Scientists want to help these individuals communicate by developing a brain machine interface to decode the commands the brain is sending to the tongue, palate, lips and larynx. New research has moved science closer by unlocking new information about how the brain encodes speech. They discovered the brain controls speech in a similar way to how it controls arm movements.
Scientists have developed a human-friendly, ultra-flexible organic sensor powered by sunlight, which acts as a self-powered heart monitor. In this study, they directly integrated a sensory device, called an organic electrochemical transistor -- a type of electronic device that can be used to measure a variety of biological functions -- into a flexible organic solar cell. Using it, they were then able to measure the heartbeats of rats and humans under bright light conditions.
Genetic causes of rare neurodevelopmental disorders vary more than previously thought, a new study finds. Researchers discovered that serious rare disorders can be affected by combinations of common genetic variants, rather than solely individual genes.
Alcohol outlets in Baltimore that sell alcohol for off-premise consumption have a stronger association with incidences of violent crimes, including homicides, aggravated assaults, sexual assaults, and robbery, than alcohol outlets in Baltimore where alcohol is bought and consumed on-site, such as bars and restaurants, a new study finds.
Obese mothers who lose weight through bariatric surgery can have safer deliveries, according to an observational study. Positive effects include fewer caesarean sections, infections, tears and hemorrhages, and fewer cases of post-term delivery or uterine inertia.
The health habits of people in a patient's social network are tied to that person's level of reported neurological disability, researchers find.